Evidence and label comparisons · WSNC nutrition education

Licorice Supplements: Glycyrrhizin Versus DGL Formulas

Licorice with glycyrrhizin and deglycyrrhizinated licorice, or DGL, are different preparations. Compare Adrenal Complex with HiPep by the exact licorice type and companion herbs rather than assuming their safety and purposes are interchangeable.

Compare the exact preparation and labeled serving

Adrenal Complex declares licorice extract with 25 mg glycyrrhizin per tablet alongside rehmannia. HiPep lists DGL licorice with chamomile and meadowsweet. Read the preparation and the full formula instead of comparing root-equivalent weights alone.

The amounts below reproduce the inspected manufacturer online panel. They describe labeled servings, not an individualized regimen. Confirm your selected package and review the full ingredient list and dietary attributes on the product page.

Declared manufacturer amounts checked October 14, 2026; compare the exact selected package
Product	Declared serving facts	Important distinction
Adrenal ComplexView product →	Declared serving factsEach Serving Size (1 Tablet) contains: Calcium 88 mg, Licorice root 12:1 extract 192.3 mg (from Glycyrrizha glabra root 2.31 g, Containing glycyrrhizin 25 mg), Rehmannia rhizome 5:1 extract 150 mg (from Rehmannia glutinosa rhizome 750 mg).	Important distinctionRecorded dietary attributes: Vegan; Vegetarian. Read the complete Adrenal Complex ingredient list and current package. The serving facts describe this formula; a shared ingredient does not make it equivalent to another product.
HiPepView product →	Declared serving factsEach Serving Size (1 Tablet) contains: Calcium 48 mg, Deglycyrrhizinized Licorice root 27.5:1 extract 125 mg (from Glycyrrhiza glabra root 3.42 g), Chamomile flower 3.5:1 extract 171.4 mg (from Matricaria recutita flower 600 mg), Meadowsweet herb 4:1 extract 125 mg (from Filipendula ulmaria herb 500 mg), Chamomile (Matricaria recutita) flower essential oil 5 mg.	Important distinctionRead the complete HiPep ingredient list and current package. The serving facts describe this formula; a shared ingredient does not make it equivalent to another product.

References: WSNC Adrenal Complex recorded label details ↗ · WSNC HiPep recorded label details ↗ · Licorice Root: Usefulness and Safety | NCCIH ↗

What the ingredient evidence can establish

NCCIH describes uncertainty about licorice alone for digestive symptoms. Findings from a gargle, topical preparation or another herbal blend do not establish the effect of an oral retail formula.

The removal of glycyrrhizin changes an important safety consideration, but it does not prove that every DGL product treats reflux or ulcers. Preparation-specific evidence remains necessary.

References: Licorice Root: Usefulness and Safety | NCCIH ↗

Review suitability, medicines and the whole formula

Glycyrrhizin can cause serious cardiovascular effects, particularly with hypertension, heart or kidney conditions or longer use. Corticosteroid interactions have been reported. Pregnancy and nursing require professional guidance; DGL should not be assumed to remove all blend-related concerns.

Ask whether the intended product contains glycyrrhizin, why it is being considered and how medicines and health history affect suitability.

References: WSNC Adrenal Complex recorded label details ↗ · WSNC HiPep recorded label details ↗ · Licorice Root: Usefulness and Safety | NCCIH ↗

Prepare a focused practitioner conversation

Bring the selected label, your reason for considering licorice, and a list of medicines and other supplements. Compare the intended outcome with the specific preparation studied, and agree how suitability and any benefit will be assessed.

Manufacturer suggested-use text checked for these products: Adrenal Complex: 1 tablet 2 - 3 times daily, or as directed. HiPep: 1 tablet 3 - 5 times daily, or as directed. Cautions: Contraindicated in known allergy to plants of the daisy family. Meadowsweet should be avoided by person hypersensitive to salicylates. Not to be used during pregnancy and lactation unless otherwise directed by a qualified health care professional.

These are separate product instructions, not one combined supplement schedule. Keep the current package directions with your practitioner plan; ingredient research does not override manufacturer labeling.

References: WSNC Adrenal Complex recorded label details ↗ · WSNC HiPep recorded label details ↗ · Licorice Root: Usefulness and Safety | NCCIH ↗

Protocol label reading

These kits contain a product compared in this guide. That ingredient match does not establish effects for the complete kit or individual suitability. Review all components with your practitioner.

Common questions

How should I compare licorice supplement labels?

Does ingredient research prove the complete formula works?

The removal of glycyrrhizin changes an important safety consideration, but it does not prove that every DGL product treats reflux or ulcers. Preparation-specific evidence remains necessary.

What should I discuss before considering licorice?

Evidence and product label sources

WSNC label links below present recorded Standard Process product information on our site. Noncommercial references explain ingredients, evidence limits and safety; they do not verify every formula amount or establish a treatment outcome for a finished product or protocol. The referenced organizations do not endorse this store.

Manufacturer nutrition-panel amounts shown here were checked October 14, 2026. Confirm the current packaging, directions and dietary information before use. Your healthcare practitioner can help assess individual suitability.

How we research products → · Prepare a practitioner conversation →