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Digestion, enzymes and microbiome support
Digestive Health Supplements
Compare enzymes, gastric support, fiber, probiotics and biliary formulas by the function they are designed to support.
43 products in this guideQuick answer
How to compare digestive health supplements
Digestive health supplements include materially different formula types such as digestive enzymes, probiotics, prebiotics, fiber, gastric-support and biliary formulas. The useful comparison is the digestive function being supported, not simply whether two products appear in the same category.
A thoughtful starting point
Understand the goal before choosing a product
Digestive products differ substantially: enzymes, hydrochloride salts, fibers, probiotics and biliary formulas are not interchangeable.
Persistent or concerning digestive symptoms deserve clinical evaluation rather than repeated supplement changes.
Practitioner-dispensed options
Search all products →Digestive Health Supplements to compare
Digestive Support
Protocol: Healthy Gastric Mucosa Support
Support for healthy gut barrier and mucosal integrity*
$214.20View details →
Digestive Support
Protocol: Healthy Gallbladder Support
Support for healthy gallbladder function and bile flow*
$252.60View details →
Digestive Support
Protocol: Gastroesophageal Function
Support for healthy gastroesophageal function*
$197.40View details →
Digestive Support
Protocol: Healthy Gut Microbiome
Support for a diverse and balanced gut microbiome*
$312.00View details →
Digestive Support
Protocol: Support for Intestinal Cleansing II
Nutritional support for intestinal cleansing, repair, and renewal*
$222.00View details →
Digestive Support
Protocol: Digestive Health During Travel
Support for digestive comfort and microbial balance while traveling*
$267.00View details →
Digestive Support
Gastrex®
Supports digestion and stimulates cleansing of upper GI tract*
$34.80View details →
Digestive Support
A-F Betafood®
A beet-centered whole-food formula with vitamin A, vitamin B6, iodine and essential fatty-acid ingredients for biliary and gallbladder support.*
From $34.20View details →
Digestive Support
Lactic Acid Yeast™
Cleanses and promotes healthy function in the lower GI tract*
$30.60View details →
Digestive Support
Multizyme®
A broad digestive-enzyme formula with pancreatin plus plant and microbial enzymes for the breakdown of proteins, carbohydrates and fats.*
From $35.40View details →
Digestive Support
Purification Product Kit with SP Complete® Dairy Free and Gastro-Fiber®
To help purify, nourish, and maintain a healthy body & weight*
$334.80View details →
Digestive Support
Purification Product Kit with SP Complete® Vanilla and Gastro-Fiber®
To help purify, nourish, and maintain a healthy body & weight*
$334.80View details →
Digestive Support
Zypan®
Digestive support combining betaine hydrochloride, pepsin and pancreatin to support normal gastric pH and healthy protein digestion.*
From $22.20View details →
Digestive Support
Gastro-Fiber®
Supports the digestive system and healthy elimination*
$31.80View details →
Digestive Support
Protocol: Children's Immune and GI Health
Foundational support for children's immune and digestive health*
$142.80View details →
Digestive Support
SP Children’s® ProSynbiotic
SP Children's ProSynbiotic is a children’s probiotic supplement which provides microbiome support, a good source of fiber, & promotes healthy bowel movements.*
$42.00View details →
Digestive Support
Golden Seal 500mg
Gastrointestinal tract mucous membrane support*
$83.40View details →
Digestive Support
Protocol: Support for Healthy Bile Acids
Nutritional support for healthy bile acid metabolism*
$250.20View details →
Digestive Support
Purification Product Kit with SP Complete® Chocolate, SP Complete® Vanilla and Gastro-Fiber®
To help purify, nourish, & maintain a healthy body & weight*
$334.80View details →
Digestive Support
ProSynbiotic
A synbiotic blend pairing four probiotic microorganisms with chicory-root inulin to support gut microbiota, regularity and intestinal health.*
From $55.20View details →
Digestive Support
Enzycore
A vegetarian microbial-enzyme and L-glutamine blend supporting digestion of fats, proteins and carbohydrates throughout the digestive tract.*
From $49.20View details →
Digestive Support
Prebiotic Inulin
Supports bone health, the immune system and gut balance*
$48.00View details →
Digestive Support
Purification Product Kit with SP Complete® and Gastro-Fiber®
To help purify, nourish, and maintain a healthy body & weight*
$334.80View details →
Digestive Support
Zymex® II
A pancreatin-free and betaine-HCl-free digestive-enzyme formula designed for gastrointestinal and meal-time digestive support.*
From $45.60View details →
Digestive Support
Betafood®
Contains beets to support digestion and intestinal function*
From $43.20View details →
Digestive Support
Purification Product Kit with SP Complete® Chocolate and Gastro-Fiber®
To help purify, nourish, and maintain a healthy body & weight*
$334.80View details →
Educational, not prescriptive. This list helps you compare formula types; it is not a diagnosis or individualized recommendation.
Explore related combinations
View all supplement kits & protocols →Supplement Kits & Protocols
Explore kits related to this health goal. Each page explains the recorded products, the nutritional question and what to discuss with your practitioner.
Foundational Nutrition
Protocol: Nutritional Support for Proton Pump Inhibitor Therapy
A proton pump inhibitor may be prescribed for a clear medical reason. This protocol concerns nutritional questions during treatment, not whether you should stop acid suppression. Discuss the medicine's indication, duration and any identified nutrient concern before assuming that everyone taking it needs the same four products.
$150.60View protocol →
Digestive Support
Protocol: Healthy Gastric Mucosa Support
The gastric mucosa is the stomach lining. A lining-focused protocol should not be confused with identifying the cause of burning, pain or nausea. This listing supports a conversation about the recorded products after considering whether symptoms need assessment and whether a nutritional plan has a clear role.
$214.20View protocol →
Digestive Support
Protocol: Healthy Gallbladder Support
Gallbladder-related symptoms and ordinary digestive discomfort are not interchangeable. Before considering this protocol, clarify whether there is an identified condition or simply a nutritional question. A product name should not lead someone with possible gallstones to self-treat instead of getting an appropriate assessment.
$252.60View protocol →
Digestive Support
Protocol: Gastroesophageal Function
Reflux-like symptoms deserve a clear description: when they occur, what triggers them and whether swallowing or other warning symptoms are involved. This protocol offers a recorded product combination to discuss, while keeping diagnosis and the management of persistent gastroesophageal symptoms separate from the shopping decision.
$197.40View protocol →
Digestive Support
Protocol: Healthy Gut Microbiome
Microbiome language can make a digestive concern sound more specific than the available evidence allows. A useful starting point is the actual bowel pattern, food tolerance and duration of symptoms. This protocol provides a combination to discuss without assuming that every digestive problem proves an imbalance needing a multi-product correction.
$312.00View protocol →
Digestive Support
Protocol: Support for Intestinal Cleansing II
The word cleansing should not imply that ordinary digestion requires a purge or that vague symptoms prove toxin accumulation. This protocol is better discussed as a specific nutritional combination. Start with bowel regularity, tolerance and the reason for considering it, rather than promising an intestinal reset.
$222.00View protocol →
Digestive Support
Protocol: Digestive Health During Travel
Travel can change food choices, meal timing and access to familiar routines. This digestive protocol is a planning discussion for that context, not permission to ignore food and water precautions. Clarify the destination, existing digestive concerns and how you would respond to illness before deciding what products to pack.
$267.00View protocol →
Digestive Support
Protocol: Children's Immune and GI Health
Children's supplement decisions should be tied to age, growth, diet and a specific concern. An immune-and-digestive bundle is not a default requirement for every child. This protocol can help a parent prepare questions for the pediatric clinician before deciding whether a coordinated combination has a useful role.
$142.80View protocol →
Digestive Support
Protocol: Support for Healthy Bile Acids
Bile acids are involved in digestion, but digestive symptoms do not automatically identify a bile-acid problem. This protocol should be considered after clarifying the actual concern and relevant medical history. It offers a product combination to discuss, rather than a diagnosis derived from discomfort after eating.
$250.20View protocol →
A kit is a combination to compare, not an individualized recommendation. Review the complete labels and overlapping ingredients before choosing.
At-a-glance comparison
How these formulas differ
Use the current product label and practitioner guidance for final selection.
The first distinction is the formula approach: gastric support, enzyme blends, microbial ingredients and fiber are different choices. Compare the declared components and directions rather than treating every gut-related product as a digestive enzyme.
| Product | Listing focus | Declared formula in brief | Label directions |
|---|---|---|---|
| Zypan®View product →Standard Process | Digestive support combining betaine hydrochloride, pepsin and pancreatin to support normal gastric pH and healthy protein digestion.* | The proprietary blend contains betaine hydrochloride, bovine pancreas Cytosol™ extract, pepsin, pancreatin, ammonium chloride, bovine spleen and ovine spleen, with cellulose and calcium stearate. | Two tablets with each meal, or as directed. Swallow the tablets whole; chewing is not recommended.Full ingredients and cautions → |
| Multizyme®View product →Standard Process | A broad digestive-enzyme formula with pancreatin plus plant and microbial enzymes for the breakdown of proteins, carbohydrates and fats.* | Standard Process listing text identifies a 360 mg proprietary blend per capsule containing date powder, defatted almond, pancreatin (3x), bromelain, organic pineapple fruit powder, papain, amylase, lipase and cellulase. Its linked Supplement Facts image identifies a 464 mg blend per capsule with pancreatin listed first. These official materials differ; confirm the version on your package with your healthcare practitioner. The capsule ingredients include gelatin. | One capsule per meal, or as directed by your healthcare practitioner.Full ingredients and cautions → |
| ProSynbioticView product →Standard Process | A synbiotic blend pairing four probiotic microorganisms with chicory-root inulin to support gut microbiota, regularity and intestinal health.* | Three capsules provide a 1.3 g total proprietary blend containing inulin (chicory root fiber), Saccharomyces boulardii (500 mg), Lactobacillus acidophilus, Lactobacillus paracasei and Bifidobacterium animalis subsp. lactis. The individual inulin amount is not disclosed. Other ingredients are cellulose, water and calcium stearate. | Three capsules per day, or as directed. Store in a cool, dry place.Full ingredients and cautions → |
| Prebiotic InulinView product →Standard Process | Supports bone health, the immune system and gut balance* | Each Serving Size (2 Teaspoons) contains: Calories 15, Total Carbohydrate 6 g, Dietary Fiber (as Inulin [Chicory root fiber]) 5 g, Total Sugars <1 g, Calcium 200 mg, Magnesium 40 mg. | Two teaspoons (scoops) per day in a shake, or as directed.Full ingredients and cautions → |
| EnzycoreView product →Standard Process | A vegetarian microbial-enzyme and L-glutamine blend supporting digestion of fats, proteins and carbohydrates throughout the digestive tract.* | One capsule lists a 555 mg proprietary blend of L-glutamine, kale, beet and twelve named enzyme activities, including lactase, alpha-galactosidase and lipase. The label does not separately quantify L-glutamine or enzyme activity units. Cellulose capsule. | One capsule three times daily with meals, or as directed by your healthcare practitioner.Full ingredients and cautions → |
| Zymex® IIView product →Standard Process | A pancreatin-free and betaine-HCl-free digestive-enzyme formula designed for gastrointestinal and meal-time digestive support.* | Two capsules list a 724 mg blend containing defatted almond, date, papain, bromelain, pineapple, amylase, cellulase and lipase. Contains almond and gelatin. The formula does not list pancreatin or betaine hydrochloride; follow its between-meal directions. | Two capsules between meals, twice daily, or as directed by your healthcare practitioner.Full ingredients and cautions → |
Choose the comparison that matters
A label-based selection path
Gastric and enzyme approaches
Does the formula list betaine hydrochloride, enzymes, or a different combination?
- Zypan®View product →
Digestive support combining betaine hydrochloride, pepsin and pancreatin to support normal gastric pH and healthy protein digestion.*
- Multizyme®View product →
A broad digestive-enzyme formula with pancreatin plus plant and microbial enzymes for the breakdown of proteins, carbohydrates and fats.*
Microbial and prebiotic ingredients
Which microbial or fiber ingredients are actually declared?
- ProSynbioticView product →
A synbiotic blend pairing four probiotic microorganisms with chicory-root inulin to support gut microbiota, regularity and intestinal health.*
- Prebiotic InulinView product →
Supports bone health, the immune system and gut balance*
Additional enzyme choices
How do the ingredient blend and serving directions differ?
- EnzycoreView product →
A vegetarian microbial-enzyme and L-glutamine blend supporting digestion of fats, proteins and carbohydrates throughout the digestive tract.*
- Zymex® IIView product →
A pancreatin-free and betaine-HCl-free digestive-enzyme formula designed for gastrointestinal and meal-time digestive support.*
Compare the approaches, then read the specific labels and individual cautions.
Source discipline
Use the right source for the right question
WSNC adds independent comparison and practitioner context. Authorized Standard Process product listings remain the source for current product positioning and labels; NIH resources provide ingredient-level background; FDA guidance explains the consumer and regulatory framework for dietary supplements.
Common questions
Digestive Health Supplements FAQ
Are Zypan and Multizyme the same kind of digestive formula?
Their recorded ingredient statements differ. Zypan lists betaine hydrochloride, pepsin and pancreatin; Multizyme lists an enzyme blend including pancreatin, bromelain, papain, amylase, cellulase and lipase. Read the full comparison and cautions before considering either.
Should I compare probiotic products and fiber by the same label numbers?
Start with what each formula contains, then the relevant label units and serving directions. A count of microbial organisms, a fiber amount and a capsule count describe different things and are not interchangeable measures.
What matters when comparing enzyme formulas?
Compare the named enzymes, declared amounts or activity information when supplied, serving instructions and allergens. A proprietary blend’s total weight alone does not establish that two products have equivalent enzyme activity.
What should I compare when researching digestive health supplements?
Digestive health supplements include materially different formula types such as digestive enzymes, probiotics, prebiotics, fiber, gastric-support and biliary formulas. The useful comparison is the digestive function being supported, not simply whether two products appear in the same category. Product placement is based on the current manufacturer listing and is intended for navigation and education, not diagnosis.
Read the label in context
Related comparisons and product guides
Zypan vs. Multizyme: ingredients, directions and cautions
Compare Zypan and Multizyme using their declared ingredients, tablet or capsule directions, almond and animal ingredient considerations, and WSNC product labels.
Read the comparison →How to read digestive supplement labels
A practical label-reading sequence for Zypan, Multizyme, enzyme blends, probiotics and fiber products: serving units, ingredient roles, allergens and cautions.
Read the guide →Gallbladder vs. Bile Acid Support Protocols
Compare Standard Process gallbladder and bile-acid kits, their shared Choline and different companions, with questions about gallbladder history and care.
Read the comparison →Travel Digestive vs. Immune Support Protocols
Compare the two Standard Process travel kits, their preparations and packing questions, alongside a practical checklist for meals, medicines and travel health.
Read the comparison →PPI Therapy and Nutrient Intake: Questions Before Supplementing
Understand the Standard Process PPI nutrition kit, distinguish a possible nutrient concern from confirmed deficiency and prepare useful questions for your prescriber.
Read the guide →Digestive Enzyme Supplements: Types and Label Guide
Understand digestive enzyme types, label details and formula differences. Compare Standard Process options and distinguish enzymes, acid ingredients and herbs.
Read the guide →Probiotic Supplements: Strains, CFUs and What to Compare
Learn how strains, CFUs and storage distinguish probiotics. Compare ProSynbiotic with prebiotic fiber using WSNC label information and research guidance.
Read the guide →Ginger Supplements: Extracts, Blend Context and Digestive Questions
Compare Ginger supplement forms, label amounts and evidence limits. Explore extracts, blend context and digestive questions with WSNC practitioner guidance.
Read the guide →Licorice Supplements: Glycyrrhizin Versus DGL Formulas
Compare Licorice supplement forms, label amounts and evidence limits. Explore glycyrrhizin versus dgl formulas with WSNC practitioner guidance.
Read the guide →Digestive Bitters Supplements: Bitter Herbs Versus Enzymes and Acid Support
Compare Digestive Bitters supplement forms, label amounts and evidence limits. Explore bitter herbs versus enzymes and acid support with WSNC practitioner guidance.
Read the guide →Betaine HCl Supplements: Acid Support, Pepsin and Undisclosed Blend Amounts
Compare Betaine HCl supplement forms, label amounts and evidence limits. Explore acid support, pepsin and undisclosed blend amounts with WSNC practitioner guidance.
Read the guide →Wormwood Supplements: Artemisia Species and Multi-Herb Formulas
Compare Wormwood supplement forms, label amounts and evidence limits. Explore artemisia species and multi-herb formulas with WSNC practitioner guidance.
Read the guide →Burdock and Dandelion Supplements: Different Roots and Complete Formula Comparisons
Compare Burdock and Dandelion supplement forms, label amounts, evidence and safety. Review formula differences and practical practitioner questions with WSNC.
Read the guide →Collinsonia Supplements: Root Amount and the Limits of Traditional Evidence
Compare Collinsonia supplement forms, label amounts and evidence limits. Explore root amount and the limits of traditional evidence with WSNC practitioner guidance.
Read the guide →Cascara Supplements: Bark Extract and Short-Term Bowel Questions
Compare Cascara supplement forms, label amounts and evidence limits. Explore bark extract and short-term bowel questions with WSNC practitioner guidance.
Read the guide →Peppermint Supplements: Enteric-Coated Oil Versus Other Digestive Formulas
Compare Peppermint supplement forms, label amounts and evidence limits. Explore enteric-coated oil versus other digestive formulas with WSNC practitioner guidance.
Read the guide →Fiber Supplements: Types and What to Compare
Compare psyllium and mixed-fiber formulas, grams per serving and evidence limits. Explore Gastro-Fiber and Whole Food Fiber with WSNC Nutrition.
Read the guide →Captioned label explainers
Watch the formula and package distinctions
Zypan and Multizyme: read the differences
A captioned comparison of Zypan and Multizyme ingredient approaches, serving directions, almond and animal ingredients, and label cautions.
Watch with the complete transcript →