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Ligaplex® II product family
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Ligaplex® II

Long-term ligament and muscle support*

Explore the bone, joint & muscle guide →
$44.40Price checked 2026-09-20
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Consult Dr. Fancher or another licensed healthcare practitioner before beginning a new supplement program.
Product overview

What to know about Ligaplex® II

Ligaplex II supports healthy connective tissue and joint function and provides vitamin A, vitamin B12 and manganese. Review the listed serving, ingredients and cautions before ordering.*

Key label facts

Two capsules list manganese 35 mg, vitamin B12 2 mcg, vitamin D 0.6 mcg and a 650 mg proprietary blend with bovine ingredients and defatted wheat germ. Contains wheat. Review the declared manganese with your practitioner; it is not a general daily-intake recommendation.

These are labeled serving facts. Follow this product’s manufacturer directions and full cautions.

  • Ligaplex II supports healthy connective tissue and joint function and provides vitamin A, vitamin B12 and manganese.
  • Review the listed ingredients and serving information for Ligaplex® II.
  • Check the manufacturer cautions and directions before use.

Ingredients and dietary attributes

Ingredient overview

Each Serving Size (2 Capsules) contains: Vitamin A 180 mcg RAE, Vitamin D 0.6 mcg, Vitamin E 0.7 mg, Vitamin B12 2 mcg, Manganese 35 mg, Sodium 10 mg. Proprietary Blend 650 mg: Nutritional yeast, carbamide, bovine bone, veal bone PMG™ extract, bovine liver, defatted wheat germ, bovine heart PMG™ extract, magnesium citrate, organic oat flour, inositol, organic pea vine juice powder, Spanish moss (Tillandsia usneoides), organic beet (root), organic sweet potato, ribonucleic acid, organic carrot, bovine liver fat extract, bovine adrenal Cytosol™ extract, bovine kidney, bovine spleen, ovine spleen, organic shiitake mushroom powder and additional ingredients listed on the current label. Other ingredients: manganese glycerophosphate, gelatin, calcium lactate, water, calcium stearate, ascorbic acid, d-alpha tocopherol (vitamin E sunflower), dicalcium phosphate, vitamin A palmitate, cyanocobalamin and cholecalciferol. Confirm the current product package for the complete formula.

Supplement education

How the FDA describes dietary supplements ↗
NIH Office of Dietary Supplements fact sheets ↗

Dietary and allergen considerations

  • Non-Soy Formula
  • Non-Dairy Formula

Contains gelatin and animal-derived tissue ingredients; the formula includes defatted wheat germ. If you are pregnant, nursing or have impaired liver function, consult your health care professional before using this product. Keep out of reach of children.

Use the ingredient statement and label on the package you receive as the current source for dietary decisions.

Nutrient references

Ingredient research context

These NIH resources explain ingredients in the formula. They do not test or endorse this product.

Review current Ligaplex® II label and listing in the WSNC inSITE store ↗ for the ingredients and nutrients in this product. The references below give ingredient or nutrient context; they do not test or endorse the formula.

  • Vitamin A

    This NIH resource provides background on vitamin a. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Vitamin A ↗

  • Vitamin C

    This NIH resource provides background on vitamin c. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Vitamin C ↗

  • Calcium

    This NIH resource provides background on calcium. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Calcium ↗

  • Magnesium

    This NIH resource provides background on magnesium. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Magnesium ↗

  • Vitamin D

    This NIH resource provides background on vitamin d. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Vitamin D ↗

  • Vitamin B12

    This NIH resource provides background on vitamin b12. Check the current product label for the ingredient form and amount; this reference does not test or endorse Ligaplex® II. NIH background: Vitamin B12 ↗

Compare the label details

Ligaplex® II label comparisons

Ligaplex® II serving amounts, ingredient forms and formula differences. Compare complete labels and manufacturer directions. A shared ingredient or health goal does not make these formulas dose-equivalent.

Compare recorded product information, then open each full product page for complete ingredients and cautions. Serving instructions are product-specific.
ProductListing focusDeclared formula in briefLabel directions
Ligaplex® IIView product →Standard ProcessLong-term ligament and muscle support*Two capsules list manganese 35 mg, vitamin B12 2 mcg, vitamin D 0.6 mcg and a 650 mg proprietary blend with bovine ingredients and defatted wheat germ. Contains wheat. Review the declared manganese with your practitioner; it is not a general daily-intake recommendation.Two capsules twice per day, or as directed.Full ingredients and cautions →
Ligaplex® IView product →Standard ProcessBone and Joint Support*Two capsules list manganese 55 mg, vitamin B12 5.8 mcg and a 770 mg proprietary blend with bovine bone, glandular ingredients and whole-food components. The manufacturer states it is not intended for long-term use. The declared manganese amount is not a general daily-intake recommendation.Two capsules per day, or as directed.Full ingredients and cautions →
Glucosamine Synergy®View product →Standard ProcessSupports healthy joint function*One capsule lists glucosamine sulfate 500 mg, manganese 1 mg and a 91 mg proprietary blend that includes Boswellia serrata and animal-derived ingredients. Contains wheat and shellfish (crab, shrimp). The blend’s individual boswellia amount is not declared.One capsule three times per day, or as directed.Full ingredients and cautions →

How we distinguish product facts from ingredient research →

Common questions

Ligaplex® II FAQ

Clear answers based on the current manufacturer listing and practitioner context.

What is Ligaplex® II for?

Ligaplex II supports healthy connective tissue and joint function and provides vitamin A, vitamin B12 and manganese.

How is Ligaplex® II used?

Two capsules twice per day, or as directed.

What is included in Ligaplex® II?

Each Serving Size (2 Capsules) contains: Vitamin A 180 mcg RAE, Vitamin D 0.6 mcg, Vitamin E 0.7 mg, Vitamin B12 2 mcg, Manganese 35 mg, Sodium 10 mg. Proprietary Blend 650 mg: Nutritional yeast, carbamide, bovine bone, veal bone PMG™ extract, bovine liver, defatted wheat germ, bovine heart PMG™ extract, magnesium citrate, organic oat flour, inositol, organic pea vine juice powder, Spanish moss (Tillandsia usneoides), organic beet (root), organic sweet potato, ribonucleic acid, organic carrot, bovine liver fat extract, bovine adrenal Cytosol™ extract, bovine kidney, bovine spleen, ovine spleen, organic shiitake mushroom powder and additional ingredients listed on the current label.

Does Ligaplex II have the same ingredients and amounts as Ligaplex I?

No. Ligaplex II declares 35 mg manganese and a 650 mg blend per two capsules, compared with Ligaplex I’s 55 mg manganese and 770 mg blend. Ligaplex II also declares wheat. Follow each product’s distinct directions and cautions, and review total manganese with your practitioner.

Source transparency

Product sources and review notes

Product details and formulas may change. Review the current manufacturer listing and the label on the package before use. The date above records a price check; it is not an editorial review date. How we research product information →